Thursday, 22 March 2012

Laboratory Investigations of Gut Function - Mark Howard

Video uploaded by Nutricentre, Jul 2010.

Summary notes:

Mark Howard is Director of Biolab Medical Unit, part of a referral laboratory.

These days, there is greater emphasis on finding the cause of a disease rather than treating only the symptoms.

Different types of gut conditions and tests:

3 gram dose of polyethylene glycol ingested. What percentage has been absorbed? Revealed in urine results over 6 hours. If malabsorption - won't appear in urine.

Gut dysbiosis - imbalances in microorganisms in gut can occur for various reasons - hormones, immune problem, stress, antibiotics, candida ... Measuring ethanol (alcohol) in the blood is an indicator that something is fermenting in the blood.

A breath test for urea - sign of helicobacter; the advantage of a breath test over a blood test is that in the blood test, antibodies for helicobacter will show up. This doesn't mean that helicobacter are present right now, thus making extensive antibiotic treatment unnecessary.

A deficiency of lactase (an enzyme required for absorption of lactose (in small intestine)) will show up by high hydrogen reading following intake of fructose.

D-lactase (D-lactic acid - different from L-lactase) - produced as a by-product of exercise, shouldn't linger in the blood. An observation by Sheedy in Australia found a greater number of D-lactase bacteria in the feces of patients with chronic fatigue. Looking for D-lactase in the blood plasma is more reliable than looking for it in feces, since feces can be sitting around in body for 24+ hours.

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